Synthesis of N-functionalized 2,3-disubstituted benzofurans/naphthofurans from para-quinone methides and isocyanides via the [4+1] annulation pathway
| Title | Synthesis of N-functionalized 2,3-disubstituted benzofurans/naphthofurans from para-quinone methides and isocyanides via the [4+1] annulation pathway |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Kale, SB, Kumar, M, Shinde, DR, Krishna, GRama, Das, U |
| Journal | Organic Chemistry Frontiers |
| Volume | 10 |
| Issue | 15 |
| Pagination | 3746-3751 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 2052-4129 |
| Abstract | A scandium triflate catalyzed [4 + 1] cycloaddition reaction of 2-hydroxy-substituted para-quinone methides and isocyanides has been developed. This operationally simple, efficient and practical protocol provides straightforward access to a variety of N-functionalized 2,3-disubstituted benzofuran/naphthofuran derivatives with broad functional group compatibility and good scalability. |
| DOI | 10.1039/d3qo00048f |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 5.4 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)