Synthesis of molluscicidal agent cyanolide a macrolactone from D-(-)-pantolactone

TitleSynthesis of molluscicidal agent cyanolide a macrolactone from D-(-)-pantolactone
Publication TypeJournal Article
Year of Publication2011
AuthorsHajare, AK, Ravikumar, V, Khaleel, S, Bhuniya, D, D. Reddy, S
JournalJournal of Organic Chemistry
Volume76
Issue3
Pagination963-966
Date PublishedFEB
ISSN0022-3263
Abstract

An efficient synthesis of potent molluscicidal agent cyanolide A, a glycosidic 16-membered macrolide, starting from D-(-)-pantolactone is reported. Highly stereoselective aldol, oxa-Michael addition, and Yamaguchi macrolactonization are the key steps in the present synthesis.

DOI10.1021/jo101782q
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)4.45
Divison category: 
Organic Chemistry