Synthesis of functionalized amino epoxides by a three-component coupling involving aziridines, arynes and aldehydes
| Title | Synthesis of functionalized amino epoxides by a three-component coupling involving aziridines, arynes and aldehydes |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Roy, T, Thangaraj, M, Gonnade, RG, Biju, AT |
| Journal | Chemical Communications |
| Volume | 52 |
| Issue | 58 |
| Pagination | 9044-9047 |
| Date Published | JAN |
| ISSN | 1359-7345 |
| Abstract | A transition-metal-free three-component coupling involving N-substituted aziridines, arynes and aldehydes resulting in the formation of trisubstituted N-aryl alpha-amino epoxides has been demonstrated. The reaction likely proceeds via the highly strained cyclic nitrogen ylide intermediates generated from aziridines and arynes. |
| DOI | 10.1039/c6cc00057f |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry