Synthesis of the C14-C29 segment of amphidinolide U utilizing a tandem dihydroxylation-S(N)2 cyclization protocol
| Title | Synthesis of the C14-C29 segment of amphidinolide U utilizing a tandem dihydroxylation-S(N)2 cyclization protocol |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Mohapatra, DK, Rahaman, H |
| Journal | Synlett |
| Issue | 6 |
| Pagination | 837-840 |
| Date Published | APR |
| Type of Article | Article |
| ISSN | 0936-5214 |
| Keywords | amphidinolide U, Cytotoxic, Nozaki-Hiyama-Kishi coupling, tandem dihydroxylation-S(N)2 cyclization, Wittig reaction |
| Abstract | The synthesis of the C14-C29 subunit of amphidinolide U is described. The key steps include the trans-2,5-disubstituted tetrahydrofurans via a highly diastereoselective and high yielding tandem dihydroxylation-S(N)2 cyclization, Wittig reaction, and Nozaki-Hiyama-Kishi coupling reaction. |
| DOI | 10.1055/s-2008-1042931 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.323 |
Divison category:
Organic Chemistry