Synthesis of bio-compatible SPION-based aqueous ferrofluids and evaluation of radiofrequency power loss for magnetic hyperthermia

TitleSynthesis of bio-compatible SPION-based aqueous ferrofluids and evaluation of radiofrequency power loss for magnetic hyperthermia
Publication TypeJournal Article
Year of Publication2010
AuthorsMary, APReena, Narayanan, TN, Sunny, V, Sakthikumar, D, Yoshida, Y, Joy, PAlias, Anantharaman, MR
JournalNanoscale Research Letters
Volume5
Issue10
Pagination1706-1711
Date PublishedOCT
ISSN1931-7573
KeywordsMagnetic heating, Magnetic hyperthermia, Magnetic relaxation, Power loss, Superparamagnetism
Abstract

Bio-compatible magnetic fluids having high saturation magnetization find immense applications in various biomedical fields. Aqueous ferrofluids of superparamagnetic iron oxide nanoparticles with narrow size distribution, high shelf life and good stability is realized by controlled chemical co-precipitation process. The crystal structure is verified by X-ray diffraction technique. Particle sizes are evaluated by employing Transmission electron microscopy. Room temperature and low-temperature magnetic measurements were carried out with Superconducting Quantum Interference Device. The fluid exhibits good magnetic response even at very high dilution (6.28 mg/cc). This is an advantage for biomedical applications, since only a small amount of iron is to be metabolised by body organs. Magnetic field induced transmission measurements carried out at photon energy of diode laser (670 nm) exhibited excellent linear dichroism. Based on the structural and magnetic measurements, the power loss for the magnetic nanoparticles under study is evaluated over a range of radiofrequencies.

DOI10.1007/s11671-010-9729-4
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.557
Divison category: 
Biochemical Sciences
Physical and Materials Chemistry