Synthesis of the antibacterial benzoquinone primin and its water-soluble analogue, primin acid

TitleSynthesis of the antibacterial benzoquinone primin and its water-soluble analogue, primin acid
Publication TypeJournal Article
Year of Publication2010
AuthorsBhattacharya, AK, Kaur, T, Ganesh, KN
JournalSynthesis-Stuttgart
Issue7
Pagination1141-1144
Date PublishedAPR
ISSN0039-7881
Keywords1, 4-benzoquinones, Antibacterial, Johnson-Claisen rearrangement, primin, primin acid
Abstract

The biologically active natural product, primin and its water-soluble acid analogue, primin acid are prepared in 34% and 25% overall yields, respectively, from a common intermediate using a Grignard reaction and a Johnson-Claisen rearrangement as the key steps.

DOI10.1055/s-0029-1218666
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.260
Divison category: 
Organic Chemistry