Synthesis and antimicrobial activity of novel oxysterols from lanosterol
| Title | Synthesis and antimicrobial activity of novel oxysterols from lanosterol |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Shingate, BB, Hazra, BG, Salunke, DB, Pore, VS, Shirazi, F, Deshpande, MV |
| Journal | Tetrahedron |
| Volume | 69 |
| Issue | 52 |
| Pagination | 11155-11163 |
| Date Published | DEC |
| ISSN | 0040-4020 |
| Keywords | Allylic oxidation, antibacterial activity, Antifungal activity, Dihydroxylation, Oxygenated steroids |
| Abstract | Chemically diverse oxysterols and their synthetic manipulations were carried out from variety of Delta(8(9)_) lanosterol derivatives and evaluated for their in vitro antimicrobial activities. Most of the synthesized oxysterols exhibited significant antifungal activity against the tested strains. (C) 2013 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tet.2013.10.090 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.817 |
Divison category:
Biochemical Sciences
Organic Chemistry