Synthesis of aculeatins A and B via iterative hydrolytic kinetic resolution
Title | Synthesis of aculeatins A and B via iterative hydrolytic kinetic resolution |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Harbindu, A, Kumar, P |
Journal | Synthesis-Stuttgart |
Issue | 9 |
Pagination | 1479-1484 |
Date Published | MAY |
ISSN | 0039-7881 |
Keywords | aculeatins, Epoxide, Hydrolytic kinetic resolution, Linchpin coupling, spirocyclization |
Abstract | A simple and concise approach for the synthesis of aculeatins A and B starting from (+/-)-epichlorohydrin is described. The synthetic strategy features Jacobsen's hydrolytic kinetic resolution and a Linchpin coupling as key steps. |
DOI | 10.1055/s-0029-1218687 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.260 |
Divison category:
Organic Chemistry