Synthesis of 4H-chromenes by an unexpected, K3PO4-mediated intramolecular rauhut–currier type reaction
| Title | Synthesis of 4H-chromenes by an unexpected, K3PO4-mediated intramolecular rauhut–currier type reaction |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Bhunia, A, Yetra, SReddy, Gonnade, RG, Biju, AT |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 14 |
| Issue | 24 |
| Pagination | 5612-5616 |
| Date Published | APR |
| Abstract | In an attempt to develop the umpolung of Michael acceptors using chalcones having an enoate moiety under N-heterocyclic carbene (NHC) catalysis, a K3PO4-mediated intramolecular Rauhut–Currier type reaction was observed. This C(sp2)–C(sp2) coupling reaction afforded the biologically important 4H-chromenes in moderate to good yields. It is likely that the enol ether functionality acts as the nucleophilic trigger in this reaction. |
| DOI | 10.1039/C6OB00654J |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.559 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry
Physical and Materials Chemistry