Synthesis of 3-ethyl-4-metyl-1h,5-dihydro-2h-pyrrol-2-one by novel palladium(ii)-catalyzed cyclization and ring-closing metathesis

TitleSynthesis of 3-ethyl-4-metyl-1h,5-dihydro-2h-pyrrol-2-one by novel palladium(ii)-catalyzed cyclization and ring-closing metathesis
Publication TypeJournal Article
Year of Publication2015
AuthorsChavan, SP, Pathak, AB, Pawar, KP
JournalSynthesis-Stuttgart
Volume47
Issue7
Pagination955-960
Date PublishedAPR
Type of ArticleArticle
ISSN0039-7881
Keywordsantidiabetic, cyclization, glimepiride, lactams, metabolite, pyrrolinone, Ring-closing metathesis
Abstract

Synthesis of 3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one is described starting from commercially available allylamine and 4-methoxybenzylamine employing palladium-catalyzed cyclization or ring-closing metathesis as the key steps.

DOI10.1055/s-0034-1379985
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.652
Divison category: 
Organic Chemistry