Synthesis of 3 alkyl and 1,3-Bis(alkyl)indolizine amides from a-bromohydroxamates
| Title | Synthesis of 3 alkyl and 1,3-Bis(alkyl)indolizine amides from a-bromohydroxamates |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Mane, KD, Bagwe, SS, More, SG, Suryavanshi, G |
| Journal | Tetrahedron Letters |
| Volume | 118 |
| Pagination | 154386 |
| Date Published | MAR |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Keywords | a -Bromohydroxamates, Amides, HFIP, Indolizine |
| Abstract | A simple and catalyst-free method has been developed for the synthesis of hindered indolizine amide derivatives from functionalized alkyl bromides. The reaction of a variety of indolizine derivatives with azaoxyallyl cations generated in situ from a-bromoamides afforded a wide range of synthetically important mono- and di-alkylated indolizine amide derivatives in good to excellent yields.@2023 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2023.154386 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.032 |
Divison category:
Chemical Engineering & Process Development
Database:
Web of Science (WoS)
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