Surface colonized silver nano particles over chitosan poly-electrolyte micro-spheres and their multi-functional behavior
| Title | Surface colonized silver nano particles over chitosan poly-electrolyte micro-spheres and their multi-functional behavior |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Prakash, B |
| Secondary Authors | Asha, S |
| Tertiary Authors | Ananth, AN |
| Subsidiary Authors | Vanithakumari, G, Okram, GS, Jose, SP, Rajan, MAJ |
| Journal | Materials Research Express |
| Volume | 5 |
| Issue | 2 |
| Pagination | 025032 |
| Date Published | FEB |
| Type of Article | Journal Article |
| ISSN | 20531591 |
| Keywords | antibacterial properties, Chitosan, Cytotoxicity, reactive oxygen species, silver nanoparticles, theranostics |
| Abstract | hitosan/tripolyphosphate polyelectrolyte (TPP) microspheres, decorated and surface functionalized with silver nanoparticles (NPs) of average diameter of 15 nm, were synthesized following a simple two-step procedure. These Ag NP-functionalized polyelectrolyte microspheres (Ag-CSPMs) are found to be biocompatible and enhancing the reactive oxygen species in curcumin with excellent anti-bacterial activity for selected Gram-positive and negative bacterial strains, making them much attractive relative to bare surface counterparts; the well-stabilized silver NPs do not form any agglomerations on the surface of the chitosan microspheres. They also show excellent cytotoxic behavior towards MCF7 cell lines, showing a half-maximal inhibitory concentration (IC50) of 32 μg ml-1. Therefore, Ag-CSPMs exhibit multi-functional ability having potential towards theranostics applications. |
| DOI | 10.1088/2053-1591/aaa3c6 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.068 |
Divison category:
Chemical Engineering & Process Development