Sugar furanoid trans-vicinal diacid as a gamma-turn inducer: synthesis and conformational study
| Title | Sugar furanoid trans-vicinal diacid as a gamma-turn inducer: synthesis and conformational study |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Vangala, M, Dhokale, SA, Gawade, RL, Pattuparambil, RR, Puranik, VG, Dhavale, DD |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 11 |
| Issue | 40 |
| Pagination | 6874-6878 |
| Date Published | OCT |
| ISSN | 1477-0520 |
| Abstract | A simple method for the synthesis of a sugar furanoid trans vicinal diacid and its incorporation into the N-terminal tetrapeptide sequence (H-Phe-Trp-Lys-Thr-OH) to get glycopeptide 8 has been described. 2D NMR and MD simulation studies of 8 clearly show that the sugar diacid adopts a gamma-turn conformation towards the N-terminus. |
| DOI | 10.1039/c3ob41462k |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.487 |
Divison category:
Center for Material Characterization (CMC)
Central NMR Facility