Studies toward the total synthesis of carba analogue of motif C OF M. TB cell wall AG complex

TitleStudies toward the total synthesis of carba analogue of motif C OF M. TB cell wall AG complex
Publication TypeJournal Article
Year of Publication2009
AuthorsGurjar, MK, Reddy, CNageswar, Kalkote, UR, Chorghade, MS
JournalHeterocycles
Volume77
Issue2
Pagination909-925
Date PublishedFEB
ISSN0385-5414
KeywordsAllylic Alkylation, desymmetrization, Fraser-Reid's Glycosidation, M. Tb Ag Complex, Mycobacterium tuberculosis
Abstract

Herein we describe the synthesis of the carba analogue of motif C of arabinogalactan complex present in M tuberculosis cell wall. Pd(0) catalyzed allylic alkylation and Fraser-Reid's glycosidation are the two key reactions that were employed for the synthesis of central glycosyl accepter unit and the glycosylation respectively.

DOI10.3987/COM-08-S(F)59
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)1.093
Divison category: 
Organic Chemistry