Studies toward the synthesis of potent anti-inflammatory peptides solomonamides A and B: synthesis of a macrocyclic skeleton and key fragment 4-amino-6-(2 `-amino-4 `-hydroxyphenyl)-3-hydroxy-2-methyl-6-oxohexanoic acid (AHMOA)
| Title | Studies toward the synthesis of potent anti-inflammatory peptides solomonamides A and B: synthesis of a macrocyclic skeleton and key fragment 4-amino-6-(2 `-amino-4 `-hydroxyphenyl)-3-hydroxy-2-methyl-6-oxohexanoic acid (AHMOA) |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Kashinath, K, Vasudevan, N, D. Reddy, S |
| Journal | Organic Letters |
| Volume | 14 |
| Issue | 24 |
| Pagination | 6222-6225 |
| Date Published | DEC |
| ISSN | 1523-7060 |
| Abstract | A first synthetic effort toward total synthesis of highly potent solomonamides is disclosed. An efficient strategy to synthesize this class of compounds, along with the synthesis of a core macrocycle (shown in red) and the key fragment AHMOA, is described. |
| DOI | 10.1021/ol303149k |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.142 |
Divison category:
Organic Chemistry