Stereoselective synthesis of spiroannulated cyclopentenones by the Pauson-Khand reaction on carbohydrate derived enynes
| Title | Stereoselective synthesis of spiroannulated cyclopentenones by the Pauson-Khand reaction on carbohydrate derived enynes |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Hotha, S, Maurya, SK, Gurjar, MK |
| Journal | Tetrahedron Letters |
| Volume | 46 |
| Issue | 32 |
| Pagination | 5329-5332 |
| Date Published | AUG |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Keywords | carbohydrates, cyclopentenone, diversity oriented synthesis, Pauson-Khand reaction |
| Abstract | The stereoselective synthesis of spiroannulated cyclopentenones by the Pauson-Khand reactions on hexose and pentose derived enynes was achieved under carbon monoxide free conditions using a stoichiometric quantity of Co-2(CO)(8). The cobalt complex of the alkyne was cleaved using dimethoxyethane-acetonitrile at 85 degrees C to furnish spiroarmulated cyclopentenones in 75-94% yields. (c) 2005 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2005.06.013 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry