Stereoselective synthesis of the C33-C44 fragment of palau'amide
| Title | Stereoselective synthesis of the C33-C44 fragment of palau'amide |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Mohapatra, DK, Nayak, S |
| Journal | Tetrahedron Letters |
| Volume | 49 |
| Issue | 5 |
| Pagination | 786-789 |
| Date Published | JAN |
| ISSN | 0040-4039 |
| Keywords | Cytotoxic, Luche's stereoselective reduction, palau'amide, Sharpless asymmetric epoxidation, Stereoselective |
| Abstract | An efficient stereoselective synthesis of the C33-C44 fragment of palau'amide is described using a Sharpless asymmetric epoxidation, a regioselective nucleophilic ring opening of the epoxide, a Grignard reaction and a Luche stereoselective reduction of a keto compound as the key steps. (C) 2007 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2007.11.200 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.618 |
Divison category:
Organic Chemistry