Stereoselective syntheses of (+)-alpha- and (-)-beta-conhydrine from L-aspartic acid
Title | Stereoselective syntheses of (+)-alpha- and (-)-beta-conhydrine from L-aspartic acid |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Pandey, SK, Kumar, P |
Journal | Tetrahedron Letters |
Volume | 46 |
Issue | 23 |
Pagination | 4091-4093 |
Date Published | JUN |
Type of Article | Article |
ISSN | 0040-4039 |
Keywords | Alkylation, conhydrine, Grignard reaction, Piperidine alkaloids, stereoselectivity |
Abstract | An efficient synthesis of (+)-alpha-conhydrine 1 and (-)-beta-conhydrine 2 has been achieved by. diastereo selective alkylation of an amino aldehyde derivative 7 with ethylmagnesium bromide or diethylzinc. (c) 2005 Elsevier Ltd. All rights reserved. |
DOI | 10.1016/j.tetlet.2005.04.013 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry