Stereoselective syntheses of (+)-alpha- and (-)-beta-conhydrine from L-aspartic acid

TitleStereoselective syntheses of (+)-alpha- and (-)-beta-conhydrine from L-aspartic acid
Publication TypeJournal Article
Year of Publication2005
AuthorsPandey, SK, Kumar, P
JournalTetrahedron Letters
Volume46
Issue23
Pagination4091-4093
Date PublishedJUN
Type of ArticleArticle
ISSN0040-4039
KeywordsAlkylation, conhydrine, Grignard reaction, Piperidine alkaloids, stereoselectivity
Abstract

An efficient synthesis of (+)-alpha-conhydrine 1 and (-)-beta-conhydrine 2 has been achieved by. diastereo selective alkylation of an amino aldehyde derivative 7 with ethylmagnesium bromide or diethylzinc. (c) 2005 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2005.04.013
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)2.347
Divison category: 
Organic Chemistry