Stereoselective formal total synthesis of novel antibiotic (-)-centrolobine
| Title | Stereoselective formal total synthesis of novel antibiotic (-)-centrolobine |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Mohapatra, DK, Pal, R, Rahaman, H, Gurjar, MK |
| Journal | Heterocycles |
| Volume | 80 |
| Issue | 1 |
| Pagination | 219-227 |
| Date Published | JAN |
| ISSN | 0385-5414 |
| Keywords | antibiotic, Centrolobine, Keck allylation, Ring-closing metathesis, Sharpless asymmetric epoxidation |
| Abstract | A concise and stereoselective formal total synthesis of (-)-centrolobine is achieved utilizing Mioskowski's Lewis acid mediated epoxide opening followed by ring-closing metathesis as the key reaction. |
| DOI | 10.3987/COM-08-S(S)1 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.093 |
Divison category:
Organic Chemistry