Stereocontrolled synthesis of Hagen's gland lactones via iterative proline catalyzed alpha-aminoxylation and oxa-Michael addition reactions

TitleStereocontrolled synthesis of Hagen's gland lactones via iterative proline catalyzed alpha-aminoxylation and oxa-Michael addition reactions
Publication TypeJournal Article
Year of Publication2015
AuthorsKauloorkar, SVandana, Jha, V, Jogdand, GF, Kumar, P
JournalRSC Advances
Volume5
Issue75
Pagination61000-61005
Date PublishedJUL
ISSN2046-2069
Abstract

A simple and efficient synthesis of Hagen's gland lactones was achieved using a sequential alpha-aminoxylation/oxa-Michael approach in a highly diastereoselective manner with assignment of relative configurations. This method was found to be applicable to the synthesis of various other isomers of Hagen's gland lactones.

DOI10.1039/c5ra10082h
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)3.289
Divison category: 
Central NMR Facility
Organic Chemistry