Simple synthesis of (+/-)-sarkomycin

TitleSimple synthesis of (+/-)-sarkomycin
Publication TypeJournal Article
Year of Publication2005
AuthorsKar, A, Argade, NP
JournalSynthesis-Stuttgart
Issue8
Pagination1234-1236
Date PublishedMAY
Type of ArticleArticle
ISSN0039-7881
Keywords(+/-)-sarkomycin synthesis, 2-hydroxymethyl-2-cyclopentenone, Michael addition, nitromethane., oxidative Nef reaction, Oxone
Abstract

A facile 6-step route to (+/-)-sarkomycin in 17% overall yield has been described via Michael addition of nitromethane to 2-hydroxymethyl-2-cyclopentenone, oxone-induced oxidative Nef reaction, and acid catalyzed dehydration.

DOI10.1055/s-2005-861877
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.652
Divison category: 
Organic Chemistry