Simple and efficient approach to 1,3-aminoalcohols: application to the synthesis of (+)-negamycin

TitleSimple and efficient approach to 1,3-aminoalcohols: application to the synthesis of (+)-negamycin
Publication TypeJournal Article
Year of Publication2007
AuthorsS. Naidu, V, Kumar, P
JournalTetrahedron Letter
Volume48
Issue22
Pagination3793-3796
Date PublishedMAY
Type of ArticleArticle
ISSN0040-4039
Abstract

A short and practical enantioselective synthesis of (+)-negamycin has been achieved in high enantio- and diastereomeric excess using an iterative Jacobsen's hydrolytic kinetic resolution as the key step. (C) 2007 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2007.03.169
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.347
Divison category: 
Organic Chemistry