Short review on the synthetic routes for the antiepileptic drug (S)-levetiracetam

TitleShort review on the synthetic routes for the antiepileptic drug (S)-levetiracetam
Publication TypeJournal Article
Year of Publication2024
AuthorsPaul, S, Bhattacharya, AK
JournalOrganic Process Research and Development
Volume28
Issue4
Pagination924-936
Date PublishedMAR
Type of ArticleReview
ISSN1083-6160
Keywordsantiepileptic drug, butyrolactam, epilepsy, levetiracetam, synthesis
Abstract

Epilepsy is a chronic disorder characterized by recurrent unpredictable seizures. Levetiracetam (Keppra) was introduced by UCB for the treatment of partial onset seizures in patients above 16 years of age diagnosed with epilepsy. This review reports synthetic strategies available for the synthesis of (S)-levetiracetam and will certainly aid the quest for the development of new routes for its synthesis.

DOI10.1021/acs.oprd.4c00002
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.4

Divison category: 
Organic Chemistry
Database: 
Web of Science (WoS)

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