Short enantioselective total synthesis of (R)- and (S)-pipecolic acid
| Title | Short enantioselective total synthesis of (R)- and (S)-pipecolic acid |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Chavan, SP, Khairnar, LB, Chavan, PN, Kalbhor, DB |
| Journal | Tetrahedron-Asymmetry |
| Volume | 25 |
| Issue | 16-17 |
| Pagination | 1246-1251 |
| Date Published | SEP |
| ISSN | 0957-4166 |
| Abstract | A convenient and practical total synthesis of (R)- and (S)-pipecolic acid has been achieved by utilizing chiral cis-aziridine-2-carboxylate as the common synthetic precursor. The synthesis involves regioselective reductive cleavage of the aziridine ring and Wittig olefination as key reactions. (C) 2014 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetasy.2014.08.001 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.88 |
Divison category:
Organic Chemistry