Short and efficient synthesis of (S)-(+)-2-(Hydroxymethyl)-6-piperidin-2-one
| Title | Short and efficient synthesis of (S)-(+)-2-(Hydroxymethyl)-6-piperidin-2-one |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Upadhyay, PK, Kumar, P |
| Journal | Synthesis-Stuttgart |
| Issue | 15 |
| Pagination | 2512-2514 |
| Date Published | AUG |
| ISSN | 0039-7881 |
| Keywords | Amino acid, Hydrogenation, L-aspartic acid, pipecolate, piperidone, Wittig reaction |
| Abstract | A concise synthesis of (S)-(+)-2-(hydroxymethyl)-6-piperidin-2-one is described that employs L-aspartic acid as chiral pool starting material and Wittig reaction as the key step. |
| DOI | 10.1055/s-0029-1218823 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.260 |
Divison category:
Organic Chemistry