Role of hydrogen bonding in cocrystals and coamorphous solids: indapamide as a case study

TitleRole of hydrogen bonding in cocrystals and coamorphous solids: indapamide as a case study
Publication TypeJournal Article
Year of Publication2019
AuthorsAllu, S, Suresh, K, Bolla, G, Mannava, MKChaitan, Nangia, A
JournalCrystengcomm
Volume21
Issue13
Pagination2043-2048
Date PublishedAPR
Type of ArticleArticle
ISSN1466-8033
Abstract

The stronger sulfonamide-pyridine (SO2NH2 center dot center dot center dot N-Py) and sulfonamide-carboxamide (SO2NH2 center dot center dot center dot O = C-NH) hydrogen bonds direct the formation of cocrystals, while the weaker sulfonamide-amine (SO2NH2 center dot center dot center dot N-H) hydrogen bond results in coamorphous products. IDP-PIP and IDP-ARG coamorphous solids exhibit remarkable stability under accelerated conditions.

DOI10.1039/c8ce01075g
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.382

Divison category: 
Organic Chemistry

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