Residue dependent hydrogen-bonding preferences in orthanilic acid-based short peptide beta-turn motifs
| Title | Residue dependent hydrogen-bonding preferences in orthanilic acid-based short peptide beta-turn motifs |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Jedhe, GS, Vijayadas, KN, Kotmale, AS, Sangtani, E, Shinde, DR, Gonnade, RG, Rajamohanan, PR, Sanjayan, GJ |
| Journal | RSC Advances |
| Volume | 6 |
| Issue | 42 |
| Pagination | 35328-35331 |
| Date Published | MAR |
| ISSN | 2046-2069 |
| Abstract | This communication describes the competition between native beta-turn (C10) and 2-aminobenzenesulfonic acid (SAnt)( orthanilic acid)-based pseudo beta-turn (C11) in their hybrid peptides. Solid-state crystal structure and solution-state NMR studies revealed that C10 and C11 can be simultaneously observed under appropriate conditions. The variable temperature NMR coefficient data suggest that the isolated C11/C14 hydrogen bond is weaker in comparison with the consecutive C10 and C11 turns. |
| DOI | 10.1039/c6ra05684a |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.289 |
Divison category:
Center for Material Characterization (CMC)
Central NMR Facility
Organic Chemistry