Ready access to densely substituted furans using Tsuji-Wacker type cyclization

TitleReady access to densely substituted furans using Tsuji-Wacker type cyclization
Publication TypeJournal Article
Year of Publication2022
AuthorsMasal, DP, Choudhury, R, Singh, A, D. Reddy, S
JournalJournal of Organic Chemistry
Volume87
Issue1
Pagination556-568
Date PublishedJAN
Type of ArticleArticle
ISSN0022-3263
Abstract

A competent method for the construction of highly substituted furans catalyzed by Pd(II) and Cu(II) chloride has been developed. The method provides easy access to di-, tri-, and tetrasubstituted furans from corresponding diols with relatively mild conditions in a unified strategy. The developed method has been successfully tested with more than 25 substrates, which resulted in furans of multiple substitution patterns with up to 84% isolated yields.

DOI10.1021/acs.joc.1c02567
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

4.198

Divison category: 
Organic Chemistry
Database: 
Web of Science (WoS)

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