Rapid access to benzoxaphospholes and their spiro analogues by a three-component coupling involving arynes, phosphines, and activated ketones
| Title | Rapid access to benzoxaphospholes and their spiro analogues by a three-component coupling involving arynes, phosphines, and activated ketones |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Bhunia, A, Roy, T, Gonnade, RG, Biju, AT |
| Journal | Organic Letters |
| Volume | 16 |
| Pagination | 5132-5135 |
| Date Published | OCT |
| Type of Article | Article |
| ISSN | 1523-7060 |
| Abstract | An operationally simple multicomponent coupling involving in situ generated arynes from 2 (trimethylsilyl)aryl triflates, phosphines, and various acyclic and cyclic activated carbonyl compounds has been developed. The reaction proceeds via a formal [3 + 2] cycloaddition mode giving access to differently substituted (spiro)benzoxaphosphole derivatives in moderate to good yields Mild reaction conditions. a broad scope. and the possibility of varying all the three-components are the notable features of the present reaction. |
| DOI | 10.1021/ol502490t |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.17 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry