Protecting group directed stereoselective reduction of an epi-inosose: efficient synthesis of epi-inositol

TitleProtecting group directed stereoselective reduction of an epi-inosose: efficient synthesis of epi-inositol
Publication TypeJournal Article
Year of Publication2011
AuthorsPatil, MT, Krishnaswamy, S, Sarmah, MP, Shashidhar, MS
JournalTetrahedron Letters
Volume52
Issue29
Pagination3756-3758
Date PublishedJUL
ISSN0040-4039
KeywordsCyclitol, Inositol, Polyol, reduction, Stereoselective
Abstract

A facile and high yielding synthesis of epi-inositol via stereoselective reduction of a pentaprotected epi-inosose is reported. Extent of stereoselectivity during the hydride reduction appears to depend on the ability of the substrate to complex with metal ions in the reducing agent. (C) 2011 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2011.05.051
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.683
Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry