Proline catalyzed direct diastereoselective 6-enolexo aldolization: toward the synthesis of the imino sugar DNJ
Title | Proline catalyzed direct diastereoselective 6-enolexo aldolization: toward the synthesis of the imino sugar DNJ |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Kumar, I, Rode, CV |
Journal | Tetrahedron-Asymmetry |
Volume | 21 |
Issue | 21-22 |
Pagination | 2703-2708 |
Date Published | NOV |
ISSN | 0957-4166 |
Abstract | A L-proline catalyzed direct diastereoselective 6-enolexo aldolization reaction of differentiating dialdehydes derived from tartaric acid is presented This organocatalytic approach provides high levels of synselectivity (dr > 10 1) with the stereocontrolled C-C bond formation between C4 and C5 intramolecularly which can serve to synthesize Imino-sugar skeleton quickly (C) 2010 Elsevier Ltd All rights reserved |
DOI | 10.1016/j.tetasy.2010.10.024 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.484 |
Divison category:
Chemical Engineering & Process Development