Practical synthesis of phthalimides and benzamides by a multicomponent reaction involving arynes, isocyanides, and CO2/H2O
Title | Practical synthesis of phthalimides and benzamides by a multicomponent reaction involving arynes, isocyanides, and CO2/H2O |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Kaicharla, T, Thangaraj, M, Biju, AT |
Journal | Organic Letters |
Volume | 16 |
Issue | 6 |
Pagination | 1728–1731 |
Date Published | MAR |
Abstract | Transition-metal-free multicomponent reactions involving arynes and isocyanides with either CO2 or H2O have been reported. With CO2 as the third component, the reactions resulted in the formation of N-substituted phthalimides. The utility of water as the third component furnished benzamide derivatives in moderate to good yields. These reactions took place under mild conditions with broad scope. |
DOI | 10.1021/ol500403x |
Funding Agency | Council of Scientific & Industrial Research (CSIR) - India |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 7.03 |
Divison category:
Organic Chemistry