Polymorph II of hydroxyurea 150 years after its first synthesis

TitlePolymorph II of hydroxyurea 150 years after its first synthesis
Publication TypeJournal Article
Year of Publication2023
AuthorsRai, SK, Tothadi, S, Arhangelskis, M, George, CP, Gonnade, RG, Nangia, AK
JournalCrystengcomm
Volume25
Issue18
Pagination2712-2716
Date PublishedMAY
Type of ArticleArticle
Abstract

A new polymorph of hydroxyurea (HU) was crystallized 150 years after its first synthesis. Due to its medicinal use in neoplastic diseases and sickle cell anemia, a high throughput screen of HU binary cocrystals was attempted. Instead of a cocrystal, an isoenergetic form II crystallized concomitantly with urea in methanol.

DOI10.1039/d3ce00163f
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.756

Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry
Database: 
Web of Science (WoS)

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