Photoinduced multicomponent regioselective synthesis of 1,4,5-trisubstituted-1,2,3-triazoles: transition metal-, azide- and oxidant-free protocol
| Title | Photoinduced multicomponent regioselective synthesis of 1,4,5-trisubstituted-1,2,3-triazoles: transition metal-, azide- and oxidant-free protocol |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Allaka, BSai, Basavoju, S, Krishna, GRama |
| Journal | Advanced Synthesis & Catalysis |
| Volume | 363 |
| Issue | 14 |
| Pagination | 3560-3565 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 1615-4150 |
| Keywords | 1, 2, 3-triazoles, 4, 5-trisubstituted-1, azide- and oxidant free protocol, Cycloaddition, milder reaction conditions, molecular diversity, Multicomponent reaction, Regioselectivity, transition metal- |
| Abstract | A transition metal- and azide-free approach is explored to synthesize 1,4,5-trisubstituted-1,2,3-triazoles under sunlight. The reaction proceeds via C-N and N-N bond formations. These regioselective 1,2,3-triazoles are obtained from isatin Schiff bases, benzaldehydes and tosylhydrazine in the presence of base. This protocol offers the structurally diverse 1,2,3-triazole derivatives with 75-90% yields. |
| DOI | 10.1002/adsc.202100321 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 5.837 |
Divison category:
Organic Chemistry