Phosphine-free manganese(II)-catalyst enables acceptorless dehydrogenative coupling of alcohols with indoles
| Title | Phosphine-free manganese(II)-catalyst enables acceptorless dehydrogenative coupling of alcohols with indoles |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Yadav, V, Balaraman, E, Mhaske, SB |
| Journal | Advanced Synthesis & Catalysis |
| Volume | 363 |
| Issue | 18 |
| Pagination | 4430-4439 |
| Date Published | SEP |
| Type of Article | Article |
| ISSN | 1615-4150 |
| Keywords | acceptorless dehydrogenation, Alcohol, Indole, manganese, phosphine-free |
| Abstract | Herein, an air-stable, molecularly defined NNN-Mn(II) pincer complex catalyzed acceptorless dehydrogenative coupling of alcohols with indoles is reported. A wide variety of symmetrical and unsymmetrical bis(indolyl)methane derivatives as well as some structurally important products such as Vibrindole A, Turbomycin B alkaloid, Antileukemic, and Anticancer agents were synthesized. Mechanistic studies illustrate the importance of the NH moiety in the complex and the crucial role of metal-ligand cooperation during catalysis. |
| DOI | 10.1002/adsc.202100621 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 5.837 |
Divison category:
Organic Chemistry