Pd-Catalyzed imine cyclization: synthesis of antimalarial natural products aplidiopsamine A, marinoquinoline A, and their potential hybrid NCLite-M1

TitlePd-Catalyzed imine cyclization: synthesis of antimalarial natural products aplidiopsamine A, marinoquinoline A, and their potential hybrid NCLite-M1
Publication TypeJournal Article
Year of Publication2012
AuthorsMahajan, JP, Suryawanshi, YR, Mhaske, SB
JournalOrganic Letters
Volume14
Issue22
Pagination5804-5807
Date PublishedNOV
Type of ArticleArticle
ISSN1523-7060
Abstract

Palladium-catalyzed cyclization of imines has been developed to construct the extremely rare 3H-pyrrolo[2,3-c]quinoline ring system for diversity oriented first total synthesis of antimalarial marine natural product Aplidiopsamine A as well as synthesis of Marinoquinoline A and potential natural product hybrid NCLite-M1.
DOI10.1021/ol302676v
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)6.142
Divison category: 
Organic Chemistry