Palladium-catalyzed oxidative cyclization of ?-allenols in the presence of TBN: access to 3(2H)-furanones
Title | Palladium-catalyzed oxidative cyclization of ?-allenols in the presence of TBN: access to 3(2H)-furanones |
Publication Type | Journal Article |
Year of Publication | 2023 |
Authors | Ghotekar, GS, Shinde, RA, Saswade, SS, Muthukrishnan, M |
Journal | Journal of Organic Chemistry |
Volume | 88 |
Issue | 7 |
Pagination | 4112-4122 |
Date Published | APR |
Type of Article | Article |
ISSN | 0022-3263 |
Keywords | Alternatively, conditions, cumbersome workup, intramolecular electrophilic, multiple reaction steps, noted examples |
Abstract | A new palladium-catalyzed oxidative cyclization of alpha-allenols is described. The readily accessible alpha-allenols participate in intra-molecular oxidative cyclization in the presence of TBN to grant access to multisubstituted 3(2H)-furanones, which are common motifs in several biologically important natural products and pharmaceuticals. |
DOI | 10.1021/acs.joc.2c024574112 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 4.198 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)
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