Palladium-catalyzed oxidative cyclization of ?-allenols in the presence of TBN: access to 3(2H)-furanones
| Title | Palladium-catalyzed oxidative cyclization of ?-allenols in the presence of TBN: access to 3(2H)-furanones |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Ghotekar, GS, Shinde, RA, Saswade, SS, Muthukrishnan, M |
| Journal | Journal of Organic Chemistry |
| Volume | 88 |
| Issue | 7 |
| Pagination | 4112-4122 |
| Date Published | APR |
| Type of Article | Article |
| ISSN | 0022-3263 |
| Keywords | Alternatively, conditions, cumbersome workup, intramolecular electrophilic, multiple reaction steps, noted examples |
| Abstract | A new palladium-catalyzed oxidative cyclization of alpha-allenols is described. The readily accessible alpha-allenols participate in intra-molecular oxidative cyclization in the presence of TBN to grant access to multisubstituted 3(2H)-furanones, which are common motifs in several biologically important natural products and pharmaceuticals. |
| DOI | 10.1021/acs.joc.2c024574112 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.198 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)