Oxidative radical-mediated addition of ethers to quinone imine ketals: an access to hemiaminals
| Title | Oxidative radical-mediated addition of ethers to quinone imine ketals: an access to hemiaminals |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | More, SG, Kamble, RB, Suryavanshi, G |
| Journal | Journal of Organic Chemistry |
| Volume | 86 |
| Issue | 3 |
| Pagination | 2107-2116 |
| Date Published | FEB |
| Type of Article | Article |
| ISSN | 0022-3263 |
| Abstract | The highly regioselective synthesis of substituted hemiaminal via addition of ethers to quinone imine ketals (QIKs) has been developed under metal-free conditions. In the presence of tetrabutylammonium chloride and potassium persulfate (K2S2O8), QIKs couple efficiently with cyclic and acyclic ethers to give hemiaminals. This strategy offers an easy access to substituted hemiaminal ethers with high functional group tolerance in good to excellent yields. |
| DOI | 10.1021/acs.joc.0c02254 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.354 |
Divison category:
Chemical Engineering & Process Development
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