Oxidant controlled regio- and stereodivergent azidohydroxylation of alkenes via I-2 catalysis
| Title | Oxidant controlled regio- and stereodivergent azidohydroxylation of alkenes via I-2 catalysis |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Prasad, PK, Reddi, RN, Sudalai, A |
| Journal | Chemical Communications |
| Volume | 51 |
| Issue | 51 |
| Pagination | 10276-10279 |
| Date Published | APR |
| ISSN | 1359-7345 |
| Abstract | A novel, I-2 catalyzed regio-and stereodivergent vicinal azidohydroxylation of alkenes leading to 1,2-azidoalcohols in high yields (up to 92%) and excellent dr (up to 98%) has been developed. This unprecedented transformation employs NaN3 and DMF as N-and O-nucleophiles respectively. The role of DMF as the O-source in the reaction has been unequivocally proven by O-18 labelling studies. |
| DOI | 10.1039/c5cc02374b |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Chemical Engineering & Process Development