Ortho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox relay catalysis
| Title | Ortho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox relay catalysis |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Sancheti, SP, Akram, MO, Roy, R, Bedi, V, Kundu, S, Patil, NT |
| Journal | Chemistry-An Asian Journal |
| Date Published | OCT |
| Type of Article | Article; Early Access |
| ISSN | 1861-4728 |
| Keywords | binary catalyst system, Gold catalysis, organocatalyst, photoredox, synthetic methodology |
| Abstract | Reported herein is an ortho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox catalysis to access highly functionalized 2-(2-hydroxyaryl)-2-alkoxy-1-arylethan-1-ones. Detailed mechanistic studies suggested a relay process, initiating with gold-catalyzed hydroalkoxylation of alkynes, to generate enol-ether followed by a key formal [4+2]-cycloaddition reaction. The successful application of the present methodology was also shown for the synthesis of benzofurans. |
| DOI | 10.1002/asia.201901275 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.698 |
Divison category:
Organic Chemistry
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