Organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin
| Title | Organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Kumar, P, Pandey, M, Gupta, P, Dhavale, DD |
| Journal | Tetrahedron Letters |
| Volume | 51 |
| Issue | 44 |
| Pagination | 5838-5839 |
| Date Published | NOV |
| ISSN | 0040-4039 |
| Keywords | Aminoxylation, Compactin, Lactone, organocatalysis, Proline |
| Abstract | An efficient synthesis of lactone moiety of compactin has been achieved. The stereogenic centers were generated by means of iterative proline-catalyzed sequential alpha-aminoxylation and Horner-Wadsworth-Emmons (HWE) olefination of aldehydes. (C) 2010 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2010.08.093 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.618 |
Divison category:
Organic Chemistry