Organocatalytic route to the synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and ravensara lactones
Title | Organocatalytic route to the synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and ravensara lactones |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Dwivedi, N, Tripathi, D, Kumar, P |
Journal | Tetrahedron-Asymmetry |
Volume | 22 |
Issue | 18-19 |
Pagination | 1749-1756 |
Date Published | OCT |
ISSN | 0957-4166 |
Abstract | An organocatalytic enantioselective synthesis of the title compounds has been achieved. The stereogenic centers were generated by the iterative use of proline catalyzed alpha-aminoxylations and HWE olefination of aldehydes while the lactone ring was constructed by ring closing metathesis. (C) 2011 Elsevier Ltd. All rights reserved. |
DOI | 10.1016/j.tetasy.2011.09.017 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.652 |
Divison category:
Organic Chemistry