Organocatalytic activation of TMSCN by basic ammonium salts for efficient cyanation of aldehydes and imines
| Title | Organocatalytic activation of TMSCN by basic ammonium salts for efficient cyanation of aldehydes and imines |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | I. Raj, VPaul, Suryavanshi, G, Sudalai, A |
| Journal | Tetrahedron Letters |
| Volume | 48 |
| Issue | 40 |
| Pagination | 7211-7214 |
| Date Published | OCT |
| Type of Article | Article |
| ISSN | 0040-4039 |
| Keywords | aldehydes, aminonitriles, cyanohydrin, cyanosilylation, multicomponent reactions, TMSCN |
| Abstract | Basic ammonium salts act as highly effective catalysts for the cyanosilylation of aldehydes and in Strecker-type aminonitrile synthesis using TMSCN as cyanide source at 25 degrees C under extremely mild conditions, affording very good to excellent yields of silylated cyanohydrins and alpha-aminonitriles. (C) 2007 Published by Elsevier Ltd. |
| DOI | 10.1016/j.tetlet.2007.07.188 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Chemical Engineering & Process Development