Novel fluorescence probe for estimation of cysteine/histidine in human blood plasma and recognition of endogenous cysteine in live Hct116 cells

TitleNovel fluorescence probe for estimation of cysteine/histidine in human blood plasma and recognition of endogenous cysteine in live Hct116 cells
Publication TypeJournal Article
Year of Publication2014
AuthorsReddy, UG, Agarwalla, H, Taye, N, Ghorai, S, Chattopadhyay, S, Das, A
JournalChemical Communications
Volume50
Issue69
Pagination9899-9902
Date PublishedSEP
ISSN1359-7345
Abstract

A new Cu(II)-complex is used as a ``Turn-On'' luminescence probe for specific detection of endogenous Cys in live Hct116 cells and Cys present in human blood plasma without any interference from other amino acids, especially GSH and Hcy. Difference in the mechanistic pathway for Cys and His recognition is discussed.

DOI10.1039/c4cc04214j
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.67
Divison category: 
Organic Chemistry