Novel, concise and efficient protocol for non-natural piperidine compounds
| Title | Novel, concise and efficient protocol for non-natural piperidine compounds |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Chavan, SP, Dumare, NB, Pawar, KP |
| Journal | RSC Advances |
| Volume | 4 |
| Issue | 62 |
| Pagination | 32594-32598 |
| Date Published | JUL |
| ISSN | 2046-2069 |
| Abstract | Formal synthesis of L-altro-1-deoxynojirimycin, cis-3-hydroxypipecolic acid along with synthesis of (R)-piperidinol and a conceptually different advanced intermediate for non-natural piperidine alkaloids is reported from cis-butene-1,4-diol. The key reactions involved are Johnson-Claisen rearrangement, Sharpless asymmetric dihydroxylation, reductive lactamization and novel regioselective elimination. |
| DOI | 10.1039/c4ra04558k |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.84 |
Divison category:
Organic Chemistry