Novel and efficient synthesis of azaarene-substituted 3-hydroxy-2-oxindoles via sp(3) C-H functionalization of 2-methyl azaarenes and (2-azaaryl)methanes over a heterogeneous, reusable silica-supported dodecatungstophosphoric acid catalyst
| Title | Novel and efficient synthesis of azaarene-substituted 3-hydroxy-2-oxindoles via sp(3) C-H functionalization of 2-methyl azaarenes and (2-azaaryl)methanes over a heterogeneous, reusable silica-supported dodecatungstophosphoric acid catalyst |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Mulla, SAbdul Rash, Pathan, MY, Chavan, SS |
| Journal | RSC Advances |
| Volume | 3 |
| Issue | 43 |
| Pagination | 20281-20286 |
| Date Published | AUG |
| Type of Article | Article |
| ISSN | 2046-2069 |
| Abstract | A novel and efficient protocol has been developed for the synthesis of azaarene-substituted 3-hydroxy-2-oxindoles via sp(3) C-H functionalization of 2-methyl azaarenes and (2-azaaryl)methanes with isatin in good to excellent yield. This is the first example in which heterogeneous, reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) catalyzed sp(3) C-H functionalization of 2-substituted azaarenes and (2-azaaryl)methanes. |
| DOI | 10.1039/c3ra43515f |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.708 |
Divison category:
Chemical Engineering & Process Development