Nickel-catalyzed direct alkynylation of C(sp2)-H bonds of amides: an “inverse sonogashira strategy” to ortho-alkynylbenzoic acids. just accepted
| Title | Nickel-catalyzed direct alkynylation of C(sp2)-H bonds of amides: an “inverse sonogashira strategy” to ortho-alkynylbenzoic acids. just accepted |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Landge, VGokulkrish, Shewale, CH, Jaiswal, G, Sahoo, MKumar, Midya, SPrasad, Balaraman, E |
| Journal | Catalysis Science & Technology |
| Volume | 6 |
| Issue | 6 |
| Pagination | 1946-1951 |
| Date Published | OCT |
| Abstract | Nickel-catalyzed direct alkynylation of C(sp2)–H bonds of amides using commercially available, inexpensive 8-aminoquinoline as a removable bidentate directing group is described. The present ortho-alkynylation has a broad substrate scope, functional group tolerance and high regiocontrol, and can be scaled up. The efficiency and selectivity of this strategy provide sustainable routes to a diverse array of ortho-alkynylbenzoic acids under Ni(II)-catalyzed conditions. |
| DOI | 10.1039/C5CY01299F |
| Funding Agency | Council of Scientific & Industrial Research (CSIR) - India |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 5.287 |
Divison category:
Catalysis and Inorganic Chemistry