NHC-Catalyzed reaction of enals with hydroxy chalcones: diastereoselective synthesis of functionalized coumarins
| Title | NHC-Catalyzed reaction of enals with hydroxy chalcones: diastereoselective synthesis of functionalized coumarins |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Bhunia, A, Patra, A, Puranik, VG, Biju, AT |
| Journal | Organic Letters |
| Volume | 15 |
| Issue | 7 |
| Pagination | 1756-1759 |
| Date Published | APR |
| ISSN | 1523-7060 |
| Abstract | The N-heterocyclic carbene-catalyzed annulation of enals with 2'-hydroxy chalcones afford cyclopentane-fused coumarin derivatives with an excellent level of diastereocontrol. The reaction tolerates a broad range of functional groups; 25 examples are given, and a preliminary mechanistic investigation is provided. |
| DOI | 10.1021/ol400562z |
| Funding Agency | Council of Scientific & Industrial Research (CSIR) - India |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.324 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry