New turn on Pd2+-specific fluorescence probe and its use as an imaging reagent for cellular uptake in Hct116 cells

TitleNew turn on Pd2+-specific fluorescence probe and its use as an imaging reagent for cellular uptake in Hct116 cells
Publication TypeJournal Article
Year of Publication2015
AuthorsReddy, UG, Ali, F, Taye, N, Chattopadhyay, S, Das, A
JournalChemical Communications
Volume51
Issue17
Pagination3649-3652
Date PublishedJAN
ISSN1359-7345
Abstract

A new coumarin-rhodamine conjugate is used as a specific probe for Pd2+ ions and this could even delineate Pd(II) from Pd(0) or Pd(IV) in aqueous buffer medium (pH similar to 7). Laser confocal microscopic studies reveal that efficient cellular internalization of this reagent helps in imaging the cellular uptake of Pd2+ as low as 0.1 ppm in Hct 116 cells. This reagent could even be used for estimation of Pd2+ in human urine samples.

DOI10.1039/c4cc10171e
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)6.567
Divison category: 
Organic Chemistry