New enantioselective synthesis of the anti-parkinson agent safinamide

TitleNew enantioselective synthesis of the anti-parkinson agent safinamide
Publication TypeJournal Article
Year of Publication2014
AuthorsReddi, A, Mujahid, M, Sasikumar, M, Muthukrishnan, M
JournalSynthesis-Stuttgart
Volume46
Issue13
Pagination1751-1756
Date PublishedJUL
Type of ArticleArticle
ISSN0039-7881
KeywordsAmides, medicinal chemistry, safinamide, stereoselective synthesis
Abstract

An alternative highly enantioselective synthesis of the anti-Parkinson agent safinamide from simple, commercially available, starting materials is described. The protocol might also be useful in the synthesis of structural variants of safinamide, such as ralfinamide or related analogues

DOI10.1055/s-0033-1341104
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.652
Divison category: 
Organic Chemistry